Evidence for the exclusive expression of functional homomeric α7 nAChRs in hypothalamic histaminergic tuberomammillary neurons in rats
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چکیده
منابع مشابه
Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury.
The need for increased sleep after traumatic brain injury is a common and disabling complaint, yet its etiology is unknown. Previous studies have demonstrated diffuse damage to various hypothalamic systems, but the integrity of the histaminergic tuberomammillary nucleus, a major arousal-promoting system located in the posterior hypothalamus, has never been examined in head trauma patients. Here...
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15 صفحه اولHyperpolarization-activated inward current in histaminergic tuberomammillary neurons of the rat hypothalamus.
1. Intracellular recordings were obtained from histaminergic tuberomammillary (TM) neurons of rat hypothalamus in an in vitro slice preparation. The properties of a time- and voltage-dependent inward current activated on hyperpolarization, Ih, were studied by use of the single-electrode voltage-clamp technique. 2. The activation curve of Ih was well fit by a sigmoidal function, with half-maxima...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 2014
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2014.01.047